About this trial
The main purpose of this study is to profile exosomes isolated from the plasma of women diagnosed with Triple Negative Breast Cancer (TNBC) during routine treatment and follow up in the oncology clinic using Nanoparticle tracking analysis (NTA) and Raman/infra-red spectroscopy. Another objective is to investigate if the individual exosome patient signature can be used as:
A) a predictive marker of response to treatment, and/or
B) a prognostic biomarker
Patient Profile
Eligible patients have either early TNBC and are receiving neoadjuvant chemotherapy or starting a new line of systemic treatment for metastatic TNBC.
Where’s this trial being run?
St Vincents University Hospital and Mater Misericordiae University Hospital
Can I join this study / trial?
The first thing you do is to talk to your doctor and/or the cancer trials research team in your hospital. The contact details for the cancer trials research units in Ireland is here.
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Click HereQuestions?
Here’s a list of questions you may have for your doctor or local cancer research team.
QuestionsSummary Data
| Name: | Exosomes in TNBC |
|---|---|
| Number: | 22-21 |
| Full Title: | Pilot longitudinal study, using nanoparticle tracking analysis, raman spectroscopy, mass spectroscopy and glycosylation analyses to profile exosomes isolated from the sera of women diagnosed with triple negative breast cancer (TNBC). |
| Principal Investigator: | Professor Michaela Higgins |
|---|---|
| Type: | Collaborative |
| Sponsor: | University College Dublin |
| Recruitment Started: |
Global: n/a Ireland: 2017 |
| Global Recruitment Target: | n/a |
|---|---|
| Ireland Recruitment Target: | 40 |