About this trial
The purpose of this study is to compare the efficacy and safety of fixed duration pirtobruitinib (LOXO-305) with VR (Arm A) compared to VR alone (Arm B) in patients with CLL/SLL who have been previously treated with at least one prior line of therapy. Participation could last up to five years.
Patient Profile
Patients with previously treated chronic lymphocytic leukemia/small lymphocytic lymphoma
Where’s this trial being run?
University Hospital Waterford and Mater Misericordiae University Hospital
Can I join this study / trial?
The first thing you do is to talk to your doctor and/or the cancer trials research team in your hospital. The contact details for the cancer trials research units in Ireland is here.
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Here’s a list of questions you may have for your doctor or local cancer research team.
QuestionsSummary Data
| Name: | BRUIN CLL-322 |
|---|---|
| Number: | 20-21-44 |
| Full Title: | A Phase 3 Open-Label, Randomized Study of Fixed Duration Pirtobrutinib (LOXO-305) Plus Venetoclax and Rituximab Versus Venetoclax and Rituximab in Previously Treated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (BRUIN CLL-322) |
| Principal Investigator: | Dr Anne Fortune |
|---|---|
| Type: | Industry Sponsored |
| Sponsor: | LOXO |
| Recruitment Started: |
Global: 20-Sep-2021 Ireland: |
| Global Recruitment Target: | 600 patients |
|---|---|
| Ireland Recruitment Target: | 2 patients |